From the USA to Africa and the UK, Stephen Fry tracks down people whose lives have been transformed by this brutal disease, including those he holds dear. Stephen meets the doctors who were instrumental in initially defining the disease, such as Professor Brian Gazzard, formerly Freddie Mercury's doctor, and Professor Michael Gottlieb, Rock Hudson's doctor. He talks to people serving jail senteces for deliberately spreading the disease, and to public figures such as writer Armistead Maupin, who are all dedicated to spreading awareness. Stephen also meets some of the earliest diagnosed people who are, miraculously, still alive. He discovers what living with HIV really means, and what the future holds for this persistent and misunderstood illness
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