A darkly amusing procedural centred on a highly skilled forensic anthropologist whose expertise lies in her uncanny ability to read clues left behind in the victim's bones. She partners with an FBI agent on murder investigations when the standard methods of identifying a body are useless.

Last season, Booth revealed his true feelings to Brennan, who told him she was not able to reciprocate, so he decided he needed to move on. In the emotional season finale, Brennan, Booth and the team each decided to take on new challenges in their lives, with Brennan and Booth both leaving Washington, D.C., for life-changing experiences and vowing to reunite one year later.

As Season Six begins, Cam finds her job as a federal medical examiner and her reputation in danger due to the politics surrounding a stalled case involving the remains of a child on her pathology table. One by one, the team members come home in order to solve the mystery behind the child's death and to preserve the reputation of one of their own. Also this season, Booth has moved on emotionally, as he told Brennan he needed to do, and has entered into a serious relationship with a war correspondent.