In New York's Hudson Valley during the 1750s, woodsman, trapper and US cavalry scout Nat 'Hawkeye' Cutler (John Hart) and his Mohican friend, Chingachgook (Lon Chaney Jr.), are more than simply friends; they are blood brothers, whose bond of loyalty endures amid hard times, adventure and the cycles of hatred and violence that characterise the tough life of the northern frontier settlements. Wherever they can, Hawkeye and Chingachgook bravely endeavour to bring wrongdoers to justice and encourage harmony and understanding.